Umbilical Cord Blood Hematopoietic Stem Cell Expansion Ex Vivo
نویسندگان
چکیده
منابع مشابه
Nanofiber Expansion of Umbilical Cord Blood Hematopoietic Stem Cells
Background The aim of this study was the ex vivo expansion of Umbilical Cord Blood hematopoietic stem cells on biocompatible nanofiber scaffolds. Materials and Methods CD133+ hematopoietic stem cells were separated from umbilical cord blood using MidiMacs (positive selection) system by means of monocolonal antibody CD133 (microbeads) subsequently, flowcytometry method was done to asses...
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Background and Objective: Umbilical Cord blood (UCB) hematopoietic stem cell (HSC) transplantation is a therapeutic approach for the treatment of malignant and non-malignant hematologic disorders due to ease of collection, lack of risk for donors and lower levels of infection. Moreover, it is considered a good alternative for bone marrow HSC transplantation. The main limitation of their use is ...
متن کاملEx Vivo Expansion of Hematopoietic Stem and Progenitor Cells from Umbilical Cord Blood
Transplantation of umbilical cord blood cells is currently widely used in modern cell therapy. However, the limited number of hematopoietic stem and progenitor cells (HSPCs) and prolonged time of recovery after the transplantation are significant limitations in the use of cord blood. Ex vivo expansion with various cytokine combinations is one of the most common approaches for increasing the num...
متن کاملImproving Umbilical Cord Blood Stem Cell Engraftment by Ex Vivo Expansion of Hematopoietic Stem and Progenitor Cells
Improving umbilical cord blood stem cell engraftment by ex vivo expansion of hematopoietic stem and progenitor cells 1. Impaired thymopoiesis is associated with severe infections after double umbilical cord blood transplantation (dUCBT). Monitoring of sjTREC + T cell recovery in dUCBT patients should therefore be considered to identify patients in need for intensified support. (this thesis) 2. ...
متن کاملnanofiber expansion of umbilical cord blood hematopoietic stem cells
background the aim of this study was the ex vivo expansion of umbilical cord blood hematopoietic stem cells on biocompatible nanofiber scaffolds. materials and methods cd133+ hematopoietic stem cells were separated from umbilical cord blood using midimacs (positive selection) system by means of monocolonal antibody cd133 (microbeads) subsequently, flowcytometry method was done to assess the pur...
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ژورنال
عنوان ژورنال: Journal of Blood Disorders & Transfusion
سال: 2013
ISSN: 2155-9864
DOI: 10.4172/2155-9864.s3-004